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Dennis J Colussi
Dennis J Colussi
Aventis Pharma
Factor Xa Inhibitor
Chemical synthesis
Biochemistry
Organic chemistry
Enzyme inhibitor
4
Papers
80
Citations
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Optimization of the β-aminoester class of factor Xa inhibitors. Part 2: Identification of FXV673 as a potent and selective inhibitor with excellent in vivo anticoagulant activity
2002
Bioorganic & Medicinal Chemistry Letters
Kevin R. Guertin
Charles J. Gardner
Scott I. Klein
Allison L Zulli
Mark Czekaj
Yong Gong
Alfred P. Spada
Daniel L Cheney
Sebastian Maignan
Jean-Pierre Guilloteau
Karen Brown
Dennis J Colussi
Valeria Chu
Christopher L Heran
Suzanne R Morgan
Ross G Bentley
Christopher T Dunwiddie
Robert J. Leadley
Henry Pauls
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Citations (48)
Benzimidazoles and isosteric compounds as potent and selective factor Xa inhibitors
2002
Bioorganic & Medicinal Chemistry Letters
Wei He
Barbara Hanney
Michael R. Myers
Stephen M. Condon
Michael R. Becker
Alfred P. Spada
Christopher J. Burns
Karen Brown
Dennis J Colussi
Valeria Chu
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Citations (6)
Optimization of the β-Aminoester class of factor Xa inhibitors. part 1: P4 and side-Chain modifications for improved In vitro potency
2002
Bioorganic & Medicinal Chemistry Letters
Mark Czekaj
Scott I. Klein
Kevin R. Guertin
Charles J. Gardner
Allison L Zulli
Henry Pauls
Alfred P. Spada
Daniel L Cheney
Karen Brown
Dennis J Colussi
Valeria Chu
Robert J. Leadley
Christopher T Dunwiddie
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Citations (16)
Nonbenzamidine Compounds as Selective Factor Xa Inhibitors
2000
Bioorganic & Medicinal Chemistry Letters
Wei He
Barbara Hanney
Michael R. Myers
Alfred P. Spada
Karen Brown
Dennis J Colussi
Valeria Chu
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Citations (10)
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