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Patrick M. O’Connor
Patrick M. O’Connor
Pfizer
Biology
G2-M DNA damage checkpoint
Molecular biology
Biochemistry
Cyclin-dependent kinase 1
3
Papers
631
Citations
0.02
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The Chk1 Protein Kinase and the Cdc25C Regulatory Pathways Are Targets of the Anticancer Agent UCN-01
2000
Journal of Biological Chemistry
Paul R. Graves
Lijia Yu
Julie K. Schwarz
Janis Gales
Edward A. Sausville
Patrick M. O’Connor
Helen Piwnica-Worms
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Citations (531)
UCN-01 abrogates G2 arrest through a Cdc2-dependent pathway that is associated with inactivation of the Wee1Hu kinase and activation of the Cdc25C phosphatase
1998
Journal of Biological Chemistry
Lijia Yu
Linda Orlandi
Pei Wang
Michael S. Orr
Adrian M. Senderowicz
Edward A. Sausville
Rosella Silvestrini
Nobumoto Watanabe
Helen Piwnica-Worms
Patrick M. O’Connor
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Citations (99)
1