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Vipulkumar Kantibhai Patel

GlaxoSmithKline

32

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282

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Differential recognition of HIV-stimulated IL-1β and IL-18 secretion through NLR and NAIP signalling in monocyte-derived macrophages.

2021 PLOS Pathogens
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Discovery of GSK251: A Highly Potent, Highly Selective, Orally Bioavailable Inhibitor of PI3Kδ with a Novel Binding Mode.

2021 Journal of Medicinal Chemistry
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PhotoAffinity Bits: A photoaffinity-based fragment screening platform for efficient identification of protein ligands.

2020 Angewandte Chemie
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Investigation of a Bicyclo[1.1.1]pentane as a Phenyl Replacement within an LpPLA2 Inhibitor.

2017 ACS Medicinal Chemistry Letters
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Composés chimiques comme inhibiteurs de l'activité kinase

2017
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Fragment-Based Approach to the Development of an Orally Bioavailable Lactam Inhibitor of Lipoprotein-Associated Phospholipase A2 (Lp-PLA2)

2016 Journal of Medicinal Chemistry
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Exploitation of a Novel Binding Pocket in Human Lipoprotein-Associated Phospholipase A2 (Lp-PLA2) Discovered through X-ray Fragment Screening.

2016 Journal of Medicinal Chemistry
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Efficient methods for enol phosphate synthesis using carbon-centred magnesium bases

2015 Organic and Biomolecular Chemistry
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Novel synthetic strategies to access borolane inhibitors of Lp-PLA2

2014
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Single‐Step Microwave‐Mediated Synthesis of Oxazoles and Thiazoles from 3‐Oxetanone: A Synthetic and Computational Study

2013 Chemistry: A European Journal
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