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Robert Elston

GlaxoSmithKline

13

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540

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Safety, tolerability and antiviral activity of the antisense oligonucleotide bepirovirsen in patients with chronic hepatitis B: a phase 2 randomized controlled trial.

2021 Nature Medicine
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A Randomized, Double‐Blind, Placebo‐Controlled, First‐Time‐in‐Human Study to Assess the Safety, Tolerability, and Pharmacokinetics of Single and Multiple Ascending Doses of GSK3389404 in Healthy Subjects

2019 Clinical pharmacology in drug development
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The HIV-1 protease substitution K55R: a protease-inhibitor-associated substitution involved in restoring viral replication

2008 Journal of Antimicrobial Chemotherapy
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Long-Term (120-Week) antiviral efficacy and tolerability of fosamprenavir/ritonavir once daily in therapy-naive patients with HIV-1 infection: An uncontrolled, open-label, single-arm follow-on study

2006 Clinical Therapeutics
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In Vitro Development of Resistance to Human Immunodeficiency Virus Protease Inhibitor GW640385

2006 Antimicrobial Agents and Chemotherapy
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GW433908/ritonavir once daily in antiretroviral therapy-naive HIV-infected patients: absence of protease resistance at 48 weeks.

2004 AIDS
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The HIV-1 protease mutation K55R is associated with the presence of the M461/L mutation

2003
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Differentiation of genotypic resistance profiles for amprenavir and lopinavir, a valuable aid for choice of therapy in protease inhibitor-experienced HIV-1-infected subjects

2003 Journal of Antimicrobial Chemotherapy
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Emergence of Resistance to Protease Inhibitor Amprenavir in Human Immunodeficiency Virus Type 1-Infected Patients: Selection of Four Alternative Viral Protease Genotypes and Influence of Viral Susceptibility to Coadministered Reverse Transcriptase Nucleoside Inhibitors

2002 Antimicrobial Agents and Chemotherapy
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The E1E4 protein of human papillomavirus type 16 associates with a putative RNA helicase through sequences in its C terminus.

2000 Journal of Virology
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