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Li Liu

National Institutes of Health

38

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Discovery and Optimization of 2H-1λ2-Pyridin-2-one Inhibitors of Mutant Isocitrate Dehydrogenase 1 for the Treatment of Cancer.

2021 Journal of Medicinal Chemistry
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Structure-Based Optimization of Small Molecule Human Galactokinase Inhibitors.

2021 Journal of Medicinal Chemistry
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Early detection of cerebrovascular pathology and protective antiviral immunity by MRI

2021 bioRxiv
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Impacts of Intralipid on Nanodrug Abraxane Therapy and on the Innate Immune System

2020 Scientific Reports
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Discovery of novel inhibitors of human galactokinase by virtual screening

2019 Journal of Computer-aided Molecular Design
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Bispecific chimeric antigen receptors targeting the CD4 binding site and high-mannose Glycans of gp120 optimized for anti–human immunodeficiency virus potency and breadth with minimal immunogenicity

2018 Cytotherapy
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Discovery and optimization of piperazine-1-thiourea-based human phosphoglycerate dehydrogenase inhibitors

2018 Bioorganic & Medicinal Chemistry
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Assessing inhibitors of mutant isocitrate dehydrogenase using a suite of pre-clinical discovery assays

2017 Scientific Reports
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UTILISATIONS DE DÉRIVÉS DE THIAZOLE EN TANT QU'INHIBITEURS MUTANTS D'IDH1 POUR LE TRAITEMENT DU CANCER

2017
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A PHGDH inhibitor reveals coordination of serine synthesis and one-carbon unit fate

2016 Nature Chemical Biology
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Citations (241)