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Dana Hilt

Tufts University

26

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408

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Effect of the Histone Deacetylase Inhibitor FRM-0334 on Progranulin Levels in Patients With Progranulin Gene Haploinsufficiency: A Randomized Clinical Trial.

2021
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A randomized single and multiple ascending dose study in healthy volunteers of LTI-291, a centrally penetrant glucocerebrosidase activator.

2021 British Journal of Clinical Pharmacology
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A Large-Scale Full GBA1 Gene Screening in Parkinson's Disease in the Netherlands.

2020 Movement Disorders
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No synergistic effect of subtherapeutic doses of donepezil and EVP-6124 in healthy elderly subjects in a scopolamine challenge model

2019 Alzheimer's & Dementia: Translational Research & Clinical Interventions
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PHASE 2A RANDOMIZED, DOUBLE-BLIND, PLACEBO-CONTROLLED TRIAL OF THE HISTONE DEACETYLASE INHIBITOR (HDACI), FRM-0334, IN ASYMPTOMATIC CARRIERS OF, OR PATIENTS WITH FRONTOTEMPORAL LOBAR DEGENERATION (FTLD) DUE TO, PROGRANULIN GENE MUTATIONS

2019 Alzheimers & Dementia
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Pharmacodynamics, Pharmacokinetics, Safety, and Tolerability of Encenicline, a Selective α7 Nicotinic Receptor Partial Agonist, in Single Ascending-dose and Bioavailability Studies

2015 Clinical Therapeutics
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A Randomized, Double-Blind, Placebo-Controlled, 24-Week, Phase 2b Outcomes Study of 3 Different Doses of Encenicline or Placebo in Subjects With Mild to Moderate Probable Alzheimer’s Disease (P7.100)

2015 Neurology
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P.3.b.015 Positive encenicline exposure-response relationships for cognition and clinical function in schizophrenia patients receiving atypical antipsychotics

2015 European Neuropsychopharmacology
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P1-1 VALIDATING THE PGSA (PLACEBO GROUP SIMULATION APPROACH) USING DATA FROM A COMPANY-SPONSORED

2015
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Poster #T94 OPTIMIZING TREATMENT AND SIGNAL DETECTION WITH EVP-6124 IN A CIAS PHASE 2B STUDY

2014 Schizophrenia Research
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