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Nicholas J. Viney

Isis Pharmaceuticals

21

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Design and Rationale of the Global Phase 3 NEURO-TTRansform Study of Antisense Oligonucleotide AKCEA-TTR-LRx (ION-682884-CS3) in Hereditary Transthyretin-Mediated Amyloid Polyneuropathy.

2021 Neurology and Therapy
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Prevalence and influence of LPA gene variants and isoform size on the Lp(a)-lowering effect of pelacarsen

2021 Atherosclerosis
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Prevalence and influence of LPA gene variants and isoform size on the Lp(a)-lowering effect of antisense oligonucleotides

2021 Atherosclerosis
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Antisense Inhibition of Prekallikrein to Control Hereditary Angioedema

2020 The New England Journal of Medicine
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Rationale and Design of NEURO-TTRansform, a Phase 3 Study to Evaluate the Efficacy and Safety of AKCEA-TTR-LRx (ION-682884) in Patients with Hereditary Transthyretin-Mediated Amyloid Polyneuropathy (2240)

2020 Neurology
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Reduction Of Plasma Lipoprotein(A) With Antisense Oligonucleotides In Human Subjects Does Not Affect Fibrinolysis

2019 Atherosclerosis
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Rationale and Design of a Phase 3 Study to Evaluate the Efficacy and Safety of ION-682884 in Patients with Transthyretin-Mediated Amyloid Cardiomyopathy (ATTR-CM)

2019 Blood
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Phase 1 Investigation of a Ligand-Conjugated Antisense Oligonucleotide with Increased Potency for the Treatment of Transthyretin Amyloidosis

2019 Journal of Cardiac Failure
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Potent reduction of plasma lipoprotein(a) with an antisense oligonucleotide in human subjects does not affect ex vivo fibrinolysis

2019 Journal of Lipid Research
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Relationship between “LDL-C”, estimated true LDL-C, apolipoprotein B-100, and PCSK9 levels following lipoprotein(a) lowering with an antisense oligonucleotide

2018 Journal of Clinical Lipidology
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Citations (38)