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Leonel Torrão

Bial

19

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Synthesis and structure–activity relationships of ionizable 1,3,4-oxadiazol-2(3H)-ones as peripherally selective FAAH inhibitors with improved aqueous solubility

2016 Pure and Applied Chemistry
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Pharmacological profile of opicapone, a third-generation nitrocatechol catechol-O-methyl transferase inhibitor, in the rat.

2015 British Journal of Pharmacology
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Effect of Opicapone, a New Catechol-O-Methyltransferase Inhibitor, in Levodopa Pharmakokinetics in the Cynomolgous Monkey

2014
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Brain and peripheral pharmacokinetics of levodopa in the cynomolgus monkey following administration of opicapone, a third generation nitrocatechol COMT inhibitor

2014 Neuropharmacology
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2.242 BRAIN AND PERIPHERAL LEVODOPA PHARMACOKINETICS IN THE CYNOMOLGUS MONKEY FOLLOWING ADMINISTRATION OF OPICAPONE, A NOVEL CATECHOL-O-METHYLTRANSFERASE INHIBITOR

2012 Parkinsonism & Related Disorders
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2.243 OPICAPONE: CHARACTERIZATION OF A NOVEL PERIPHERAL LONG-ACTING CATECHOL-O-METHYLTRANSFERASE INHIBITOR

2012 Parkinsonism & Related Disorders
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Design, synthesis, and structure–activity relationships of 1,3,4-oxadiazol-2(3H)-ones as novel FAAH inhibitors

2011 MedChemComm
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Original article Chronopharmacology of nebicapone, a new catechol-O-methyltransferase inhibitor

2010 Current Medical Research and Opinion
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Discovery of a Long-Acting, Peripherally Selective Inhibitor of Catechol-O-methyltransferase

2010 Journal of Medicinal Chemistry
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Species differences in pharmacokinetic and pharmacodynamic properties of nebicapone

2009 Biochemical Pharmacology
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Citations (9)