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Qun Niu
Qun Niu
Shenyang Pharmaceutical University
Chemistry
Biochemistry
Histone deacetylase inhibitor
Vorinostat
Structure–activity relationship
4
Papers
46
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Design, synthesis and biological evaluation of dual Bcl-2/Mcl-1 inhibitors bearing 2-(1H-indol-4-yl)benzoic acid scaffold.
2021
Bioorganic & Medicinal Chemistry Letters
Qun Niu
Hongguang Deng
Zhang Zhenwei
Qinhao Xu
Shenglin Luan
Min Huang
Dan Liu
Linxiang Zhao
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Identification of N-(6-mercaptohexyl)-3-(4-pyridyl)-1H-pyrazole-5-carboxamide and its disulfide prodrug as potent histone deacetylase inhibitors with in vitro and in vivo anti-tumor efficacy
2016
European Journal of Medicinal Chemistry
Jiachen Wen
Yu Bao
Qun Niu
Jinyu Yang
Yinbo Fan
Jinhua Li
Yongkui Jing
Linxiang Zhao
Dan Liu
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Synthesis, biological evaluation and molecular modeling studies of psammaplin A and its analogs as potent histone deacetylases inhibitors and cytotoxic agents
2016
Bioorganic & Medicinal Chemistry Letters
Jiachen Wen
Yu Bao
Qun Niu
Jiang Liu
Jinyu Yang
Wanqiao Wang
Tao Jiang
Yinbo Fan
Kun Li
Jian Wang
Linxiang Zhao
Dan Liu
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Citations (9)
Novel thiol-based histone deacetylase inhibitors bearing 3-phenyl-1H-pyrazole-5-carboxamide scaffold as surface recognition motif: Design, synthesis and SAR study
2016
Bioorganic & Medicinal Chemistry Letters
Jiachen Wen
Qun Niu
Jiang Liu
Yu Bao
Jinyu Yang
Shenglin Luan
Yinbo Fan
Dan Liu
Linxiang Zhao
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Citations (15)
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