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Maria Ana Ghetie

University of Texas Southwestern Medical Center

31

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1691

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Targeting mammalian target of rapamycin to both downregulate and disable the P-glycoprotein pump in multidrug-resistant B-cell lymphoma cell lines

2009 Leukemia & Lymphoma
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Generation of multidrug resistant lymphoma cell lines stably expressing P-glycoprotein.

2008 Oncology Reports
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Rituximab but not other anti-CD20 antibodies reverses multidrug resistance in 2 B lymphoma cell lines, blocks the activity of P-glycoprotein (P-gp), and induces P-gp to translocate out of lipid rafts

2006 Journal of Immunotherapy
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The Evaluation of Recombinant, Chimeric, Tetravalent Antihuman CD22 Antibodies

2004 Clinical Cancer Research
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An anti-CD19 antibody inhibits the interaction between P-glycoprotein (P-gp) and CD19, causes P-gp to translocate out of lipid rafts, and chemosensitizes a multidrug-resistant (MDR) lymphoma cell line

2004 Blood
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Genetic engineering of an immunotoxin to eliminate pulmonary vascular leak in mice

2003 Nature Biotechnology
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Targeting Multiple Her-2 Epitopes with Monoclonal Antibodies Results in Improved Antigrowth Activity of a Human Breast Cancer Cell Line in Vitro and in Vivo

2002 Clinical Cancer Research
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Homodimers but not monomers of Rituxan (chimeric anti-CD20) induce apoptosis in human B-lymphoma cells and synergize with a chemotherapeutic agent and an immunotoxin

2001 Blood
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The Combined Use of an Immunotoxin and a Radioimmunoconjugate to Treat Disseminated Human B-Cell Lymphoma in Immunodeficient Mice

2000 Clinical Cancer Research
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Anti-CD19 Antibodies Inhibit the Function of the P-gp Pump in Multidrug-resistant B Lymphoma Cells

1999 Clinical Cancer Research
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Citations (32)