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Takeshi Yamasaki
Takeshi Yamasaki
Takeda Pharmaceutical Company
Chemistry
Pyrrole
Medicinal chemistry
hERG
Somatostatin receptor
7
Papers
21
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Discovery of novel 5-oxa-2,6-diazaspiro[3.4]oct-6-ene derivatives as potent, selective, and orally available somatostatin receptor subtype 5 (SSTR5) antagonists for treatment of type 2 diabetes mellitus
2017
Bioorganic & Medicinal Chemistry
Hideki Hirose
Takeshi Yamasaki
Masaki Ogino
Ryo Mizojiri
Yumiko Tamura-Okano
Hiroaki Yashiro
Yo Muraki
Yoshihide Nakano
Jun Sugama
Akito Hata
Shinji Iwasaki
Masanori Watanabe
Tsuyoshi Maekawa
Shizuo Kasai
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Discovery of novel somatostatin receptor subtype 5 (SSTR5) antagonists: Pharmacological studies and design to improve pharmacokinetic profiles and human Ether-a-go-go-related gene (hERG) inhibition
2017
Bioorganic & Medicinal Chemistry
Takeshi Yamasaki
Hideki Hirose
Tohru Yamashita
Nobuyuki Takakura
Sachie Morimoto
Takashi Nakahata
Asato Kina
Yoshihide Nakano
Yumiko Okano Tamura
Jun Sugama
Tomoyuki Odani
Yuji Shimizu
Shinji Iwasaki
Masanori Watanabe
Tsuyoshi Maekawa
Shizuo Kasai
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Dérivés de spiro azétidine isoxazole et leur utilisation en tant qu'antagonistes de sstr5
2014
Shizuo Kasai
Masaki Ogino
Ryo Mizojiri
Takeshi Yamasaki
Hideki Hirose
Nobuyuki Takakura
Tohru Yamashita
Sachie Morimoto
Takashi Nakahata
Asato Kina
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Verfahren zur herstellung einer pyrrolverbindung
2010
Tomomi Ikemoto
Hideya Mizufune
Toshiaki Nagata
Misayo Sera
Naohiro Fukuda
Takeshi Yamasaki
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Process for producing compound of pyrrole
2010
Tomomi Ikemoto
Hideya Mizufune
Toshiaki Nagata
Misayo Sera
Naohiro Fukuda
Takeshi Yamasaki
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