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James Koropatnick

University of Western Ontario
Lawson Health Research Institute

135

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Reduced CD5 on CD8+ T Cells in Tumors but Not Lymphoid Organs Is Associated With Increased Activation and Effector Function.

2021 Frontiers in Immunology
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CD5 blockade enhances ex vivo CD8+ T cell activation and tumour cell cytotoxicity

2020 European Journal of Immunology
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CD8+ T tumour-infiltrating lymphocytes lacking CD5 cell surface expression exhibited increased levels of activation and exhaustion

2020 European Journal of Cancer
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Abstract 917: Functional blocking of CD5 on T cells to enhance the efficacy of therapeutic PD-1 blockade in treatment of mouse 4T1 breast tumors

2020 Immunology
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miRNA-5119 regulates immune checkpoints in dendritic cells to enhance breast cancer immunotherapy

2020 Cancer Immunology, Immunotherapy
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Table S1. miRNA that are differentially expressed in CD8+PD-1+ vs. CD8+PD-1- T cells from miR-149-3p reverses CD8+ T-cell exhaustion by reducing inhibitory receptors and promoting cytokine secretion in breast cancer cells

2019
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DIY: Visualizing the immune landscape of tumors using transcriptome and methylome data

2019 Methods in Enzymology
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Supplementary material from "miR-149-3p reverses CD8 + T-cell exhaustion by reducing inhibitory receptors and promoting cytokine secretion in breast cancer cells"

2019
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miR-149-3p reverses CD8+ T-cell exhaustion by reducing inhibitory receptors and promoting cytokine secretion in breast cancer cells

2019 Open Biology
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504PAVID200 neutralizes TGF-beta1 and -beta3, the principal immunosuppressive TGF-beta isoforms overexpressed by tumours, and sensitizes tumours to immune checkpoint inhibitors

2019 Annals of Oncology
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