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Emily M. Cheney

Harvard University

4

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Abstract A105: PARP inhibition modulates the infiltration, phenotype, and function of tumor-associated macrophages (TAMs) in BRCA-associated breast cancer and can be augmented by harnessing the antitumor potential of TAMs

2020 Cancer immunology research
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860 Targeting immunosuppressive macrophages overcomes PARP-inhibitor resistance in BRCA1-associated triple-negative breast cancer

2020 Journal for ImmunoTherapy of Cancer
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Combination therapy targeting both innate and adaptive immunity improves survival in a pre-clinical model of ovarian cancer

2019 Journal for ImmunoTherapy of Cancer
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PARP inhibitor efficacy depends on CD8+ T cell recruitment via intratumoral STING pathway activation in BRCA-deficient models of triple-negative breast cancer

2019 Cancer Discovery
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