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Min Zhong

Sunesis Pharmaceuticals

16

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641

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Utilizing structure based drug design and metabolic soft spot identification to optimize the in vitro potency and in vivo pharmacokinetic properties leading to the discovery of novel reversible Bruton's tyrosine kinase inhibitors.

2021 Bioorganic & Medicinal Chemistry
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Discovery and Development of Potent LFA-1/ICAM-1 Antagonist SAR 1118 as an Ophthalmic Solution for Treating Dry Eye

2012 ACS Medicinal Chemistry Letters
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Heteroaryl-btk-hemmer

2010
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Inhibiteurs hétéroaryles de btk

2010
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Discovery of tetrahydroisoquinoline (THIQ) derivatives as potent and orally bioavailable LFA-1/ICAM-1 antagonists.

2010 Bioorganic & Medicinal Chemistry Letters
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Water-soluble prodrugs of an Aurora kinase inhibitor.

2009 Bioorganic & Medicinal Chemistry Letters
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Discovery of a potent and selective aurora kinase inhibitor.

2008 Bioorganic & Medicinal Chemistry Letters
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Aminoethylenes: a tetrahedral intermediate isostere yielding potent inhibitors of the aspartyl protease BACE-1.

2006 Journal of Medicinal Chemistry
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As aurora kinase inhibitors useful thienopyrimidines

2005
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Thienopyrimidines utiles en tant qu'inhibiteurs des kinases aurora

2005
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