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Derek K. O’Flaherty
Derek K. O’Flaherty
Howard Hughes Medical Institute
RNA
Chemistry
Biochemistry
Primer (molecular biology)
Primer extension
5
Papers
221
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Prebiotically Plausible ‘Patching’ of RNA Backbone Cleavage Through a 3′-5′ Pyrophosphate Linkage
2019
Journal of the American Chemical Society
Tom H. Wright
Constantin Giurgiu
Wen Zhang
Aleksandar Radakovic
Derek K. O’Flaherty
Lijun Zhou
Jack W. Szostak
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Citations (12)
Inosine, but none of the 8-oxo-purines, is a plausible component of a primordial version of RNA
2018
Proceedings of the National Academy of Sciences of the United States of America
Seohyun Chris Kim
Derek K. O’Flaherty
Lijun Zhou
Victor S. Lelyveld
Jack W. Szostak
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Citations (35)
Copying of Mixed-Sequence RNA Templates inside Model Protocells
2018
Journal of the American Chemical Society
Derek K. O’Flaherty
Neha P. Kamat
Fatima N. Mirza
Li Li
Noam Prywes
Jack W. Szostak
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Citations (55)
A Mechanistic Explanation for the Regioselectivity of Nonenzymatic RNA Primer Extension
2017
Journal of the American Chemical Society
Constantin Giurgiu
Li Li
Derek K. O’Flaherty
Chun Pong Tam
Jack W. Szostak
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Citations (16)
Enhanced Nonenzymatic RNA Copying with 2-Aminoimidazole Activated Nucleotides
2017
Journal of the American Chemical Society
Li Li
Noam Prywes
Chun Pong Tam
Derek K. O’Flaherty
Victor S. Lelyveld
Enver Cagri Izgu
Ayan Pal
Jack W. Szostak
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Citations (103)
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