author-photo

Stephen E. Clarke

GlaxoSmithKline

33

Papers

2604

Citations

Citation Trend

Filter By

Papers (25) Sort By

Journal Conference Others

Towards depersonalized abacavir therapy: chemical modification eliminates HLA-B*57 : 01-restricted CD8+ T-cell activation.

2015 AIDS
Show All
- Source
- Cite
- Save
Citations (12)
An integrated reactive metabolite evaluation approach to assess and reduce safety risk during drug discovery and development

2011 Chemico-Biological Interactions
Show All
- Source
- Cite
- Save
Citations (19)
Managing the challenge of chemically reactive metabolites in drug development

2011 Nature Reviews Drug Discovery
Show All
- Source
- Cite
- Save
Citations (350)
Cytochrome P450: Structure, Function, and Application in Drug Discovery and Development

2010
- Ramesh B. Bambal
- Stephen E. Clarke
Show All
- Source
- Cite
- Save
Citations (3)
Multiple adduction reactions of nitroso sulfamethoxazole with cysteinyl residues of peptides and proteins: implications for hapten formation.

2009 Chemical Research in Toxicology
Show All
- Source
- Cite
- Save
Citations (71)
Sulfamethoxazole and Its Metabolite Nitroso Sulfamethoxazole Stimulate Dendritic Cell Costimulatory Signaling

2007 Journal of Immunology
Show All
- Source
- Cite
- Save
Citations (106)
Investigation of the immunogenicity of diclofenac and diclofenac metabolites.

2007 Toxicology Letters
Show All
- Source
- Cite
- Save
Citations (46)
Activation of T cells by carbamazepine and carbamazepine metabolites

2006 The Journal of Allergy and Clinical Immunology
Show All
- Source
- Cite
- Save
Citations (121)
CYTOCHROME P450 GENE INDUCTION IN RATS EX VIVO ASSESSED BY QUANTITATIVE REAL-TIME REVERSE TRANSCRIPTASE-POLYMERASE CHAIN REACTION (TAQMAN)

2006 Drug Metabolism and Disposition
Show All
- Source
- Cite
- Save
Citations (48)
Formation and protein binding of the acyl glucuronide of a leukotriene B4 antagonist (SB-209247): relation to species differences in hepatotoxicity.

2004 Drug Metabolism and Disposition
Show All
- Source
- Cite
- Save
Citations (10)