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Sarah S. Darwish
Sarah S. Darwish
German University in Cairo
Biochemistry
Chemistry
Kinase
Potency
NF-κB
4
Papers
34
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Development of novel 2,4-bispyridyl thiophene–based compounds as highly potent and selective Dyrk1A inhibitors. Part I: Benzamide and benzylamide derivatives
2018
European Journal of Medicinal Chemistry
Sarah S. Darwish
Mohammad Abdel-Halim
Mohamed Salah
Ashraf H. Abadi
Walter Becker
Matthias Engel
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Citations (6)
Development of novel amide–derivatized 2,4-bispyridyl thiophenes as highly potent and selective Dyrk1A inhibitors. Part II: Identification of the cyclopropylamide moiety as a key modification
2018
European Journal of Medicinal Chemistry
Sarah S. Darwish
Mohammad Abdel-Halim
Ahmed K. ElHady
Mohamed Salah
Ashraf H. Abadi
Walter Becker
Matthias Engel
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Citations (4)
First Bispecific Inhibitors of the Epidermal Growth Factor Receptor Kinase and the NF-κB Activity As Novel Anticancer Agents.
2017
Journal of Medicinal Chemistry
Mostafa M. Hamed
Sarah S. Darwish
Jennifer Herrmann
Ashraf H. Abadi
Matthias Engel
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Citations (16)
Pharmacological inhibition of protein kinase C (PKC)ζ downregulates the expression of cytokines involved in the pathogenesis of chronic obstructive pulmonary disease (COPD).
2016
European Journal of Pharmaceutical Sciences
Mohammad Abdel-Halim
Sarah S. Darwish
Ahmed K. ElHady
Jessica Hoppstädter
Ashraf H. Abadi
Rolf W. Hartmann
Alexandra K. Kiemer
Matthias Engel
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Citations (8)
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