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Eckhard Ficker
Eckhard Ficker
MetroHealth
QT interval
hERG
Long QT syndrome
Ether-A-Go-Go Potassium Channels
Mutation
4
Papers
157
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The variant hERG/R148W associated with LQTS is a mutation that reduces current density on co-expression with the WT
2014
Gene
Asma Mechakra
Yohann Vincent
Philippe Chevalier
Gilles Millat
Eckhard Ficker
Marek Jastrzębski
Hugo Poulin
Valérie Pouliot
Mohamed Chahine
Georges Christé
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Citations (4)
Molecular coupling in the human ether-a-go-go-related gene-1 (hERG1) K + channel inactivation pathway
2011
Journal of Biological Chemistry
Tania Ferrer
Julio F. Cordero-Morales
Marcelo Arias
Eckhard Ficker
David Medovoy
Eduardo Perozo
Martin Tristani-Firouzi
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Citations (12)
A new C-terminal hERG mutation A915fs+47X associated with symptomatic LQT2 and auditory-trigger syncope.
2008
Heart Rhythm
Georges Christé
Olivier Thériault
Mohamed Chahine
Gilles Millat
Claire Rodriguez-Lafrasse
Robert Rousson
Isabelle Deschênes
Eckhard Ficker
Philippe Chevalier
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Citations (13)
HERG-Lite: a novel comprehensive high-throughput screen for drug-induced hERG risk.
2005
Journal of Pharmacological and Toxicological Methods
Barbara A. Wible
Peter Hawryluk
Eckhard Ficker
Yuri A. Kuryshev
Glenn E. Kirsch
Arthur M. Brown
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Citations (128)
1