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Agnès Amador

Merck & Co.

8

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Development and Scale-Up of a Manufacturing Route for the Non-nucleoside Reverse Transcriptase Inhibitor GSK2248761A (IDX-899): Synthesis of an Advanced Key Chiral Intermediate

2018 Organic Process Research & Development
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Synthesis of potent and broad genotypically active NS5B HCV non-nucleoside inhibitors binding to the thumb domain allosteric site 2 of the viral polymerase.

2016 Bioorganic & Medicinal Chemistry Letters
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Discovery of the Aryl-phospho-indole IDX899, a Highly Potent Anti-HIV Non-nucleoside Reverse Transcriptase Inhibitor.

2016 Journal of Medicinal Chemistry
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Synthesis and biological evaluation of aryl-phospho-indole as novel HIV-1 non-nucleoside reverse transcriptase inhibitors.

2011 Journal of Medicinal Chemistry
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Synthesis of 2'- C -Methylcytidine and 2'- C -Methyluridine Derivatives Modified in the 3'-Position as Potential Antiviral Agents

2006 Collection of Czechoslovak Chemical Communications
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Nm 283, an efficient prodrug of the potent anti-HCV agent 2'-C-methylcytidine.

2005 Nucleosides, Nucleotides & Nucleic Acids
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