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Graeme R. Grimes

University of Edinburgh

23

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1004

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Structural variants at the BRCA1/2 loci are a common source of homologous repair deficiency in high grade serous ovarian carcinoma.

2021 Clinical Cancer Research
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Characterisation of a nucleo-adhesome

2021 bioRxiv
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Identification and functional modelling of plausibly causative cis-regulatory variants in a highly-selected cohort with X-linked intellectual disability.

2021 PLOS ONE
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Human centromere formation activates transcription and opens chromatin fibre structure

2021 bioRxiv
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Oral vitamin D supplementation induces transcriptomic changes in rectal mucosa that are linked to anti-tumour effects

2021 BMC Medicine
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Cornelia de Lange syndrome-associated mutations cause a DNA damage signalling and repair defect.

2021 Nature Communications
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Oral Vitamin D supplementation induces transcriptomic changes in rectal mucosa that are consistent with anti-tumour effects.

2021 medRxiv
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Differential genetic influences over colorectal cancer risk and gene expression in large bowel mucosa.

2021 International Journal of Cancer
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In vivo modelling of patient genetic heterogeneity identifies concurrent Wnt and PI3K activity as a potent driver of invasive cholangiocarcinoma growth

2021 bioRxiv
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Functional Predictors of Causative Cis-Regulatory Mutations in Mendelian Disease

2020 bioRxiv
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