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Takuya Orita
Takuya Orita
Japan Tobacco
Molecular biology
Biology
Binding site
Stereochemistry
Pyruvate dehydrogenase complex
4
Papers
167
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Structure-based drug design of novel and highly potent pyruvate dehydrogenase kinase inhibitors
2021
Bioorganic & Medicinal Chemistry
Yuki Bessho
Tatsuo Akaki
Yoshinori Hara
Maki Yamakawa
Shingo Obika
Genki Mori
Minoru Ubukata
Katsutaka Yasue
Yoshitomi Nakane
Yasuo Terasako
Takuya Orita
Satoki Doi
Tomoko Iwanaga
Ayumi Fujishima
Tsuyoshi Adachi
Hiroshi Ueno
Takahisa Motomura
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Fragment-based lead discovery to identify novel inhibitors that target the ATP binding site of pyruvate dehydrogenase kinases
2021
Bioorganic & Medicinal Chemistry
Tatsuo Akaki
Yuki Bessho
Takashi Ito
Fujioka Shingo
Minoru Ubukata
Genki Mori
Kenji Yamanaka
Takuya Orita
Satoki Doi
Tomoko Iwanaga
Kazutaka Ikegashira
Yoshiji Hantani
Isao Nakanishi
Tsuyoshi Adachi
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Citations (1)
Molecular Cloning, Genomic Structure, and Expression Analysis of MUC20, a Novel Mucin Protein, Up-regulated in Injured Kidney
2004
Journal of Biological Chemistry
Toshio Higuchi
Takuya Orita
Setsuko Nakanishi
Ken Katsuya
Hirotaka Watanabe
Yoshiki Yamasaki
Iwao Waga
Toyomichi Nanayama
Yoshihisa Yamamoto
William E. Munger
Hong-Wei Sun
Ronald J. Falk
John Charles Jennette
David A. Alcorta
Huiping Li
Tadashi Yamamoto
Yutaka Saito
Motonao Nakamura
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Citations (130)
MUC20 suppresses the hepatocyte growth factor-induced Grb2-Ras pathway by binding to a multifunctional docking site of met.
2004
Molecular and Cellular Biology
Toshio Higuchi
Takuya Orita
Ken Katsuya
Yoshiki Yamasaki
Kiyotaka Akiyama
Huiping Li
Tadashi Yamamoto
Yutaka Saito
Motonao Nakamura
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Citations (36)
1