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Anne Ast

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Establishment of a FRET-based Aggregate Seeding Assay to study the pathogenic role of self-replicating mutant HTT fibrils in Huntington’s disease

2019
- Anne Ast
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Self-assembly of mutant huntingtin exon-1 fragments into large complex fibrillar structures involves nucleated branching

2018 bioRxiv
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mHTT Seeding Activity: A Marker of Disease Progression and Neurotoxicity in Models of Huntington's Disease

2018 Molecular Cell
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A Filter Retardation Assay Facilitates the Detection and Quantification of Heat-Stable, Amyloidogenic Mutant Huntingtin Aggregates in Complex Biosamples

2018 Methods of Molecular Biology
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