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Christopher A. Callahan

Genentech

9

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2296

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Neuropilin-2 expression in cancer

2012 Histopathology
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Abstract LB-1: An investigator-initiated, phase II randomized, double-blind, placebo-controlled trial of GDC-0449 for prevention of BCCs in basal cell nevus syndrome (BCNS) patients.gg

2011 Cancer Research
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Targeting Superficial or Nodular Basal Cell Carcinoma with Topically Formulated Small Molecule Inhibitor of Smoothened

2011 Clinical Cancer Research
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Abstract A44: Predictive biomarkers of efficacy to the hedgehog pathway inhibitor, GDC‐0449, in advanced basal cell carcinoma and medulloblastoma in phase I studies

2009 Molecular Cancer Therapeutics
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Hedgehog signaling is restricted to the stromal compartment during pancreatic carcinogenesis

2009 Proceedings of the National Academy of Sciences of the United States of America
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Smoothened mutation confers resistance to a Hedgehog pathway inhibitor in medulloblastoma.

2009 Science
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Treatment of medulloblastoma with hedgehog pathway inhibitor GDC-0449

2009 The New England Journal of Medicine
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Blocking of DLL4/Notch signaling deregulates tumor angiogenesis

2007 Cancer Research
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