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Akira Inoue

St. Jude Children's Research Hospital

16

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701

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A genetic mouse model with postnatal Nf1 and p53 loss recapitulates the histology and transcriptome of human malignant peripheral nerve sheath tumor

2021 bioRxiv
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Structures of REV1 UBM2 Domain Complex with Ubiquitin and with a Small-Molecule that Inhibits the REV1 UBM2–Ubiquitin Interaction

2018 Journal of Molecular Biology
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Identification of the first small-molecule inhibitor of the REV7 DNA repair protein interaction.

2016 Bioorganic & Medicinal Chemistry
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Transient myeloproliferative disorder with partial trisomy 21.

2015 Pediatric Blood & Cancer
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A novel assay revealed that ribonucleotide reductase is functionally important for interstrand DNA crosslink repair.

2015 Bioorganic & Medicinal Chemistry
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Roles of ChlR1 DNA helicase in replication recovery from DNA damage.

2013 Experimental Cell Research
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Small molecule inhibitors of PCNA/PIP-box interaction suppress translesion DNA synthesis.

2013 Bioorganic & Medicinal Chemistry
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Mammalian ChlR1 has a role in heterochromatin organization

2011 Experimental Cell Research
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Perturbation of HP1 localization and chromatin binding ability causes defects in sister-chromatid cohesion.

2008 Mutation Research-genetic Toxicology and Environmental Mutagenesis
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Loss of ChlR1 Helicase in Mouse Causes Lethality Due to the Accumulation of Aneuploid Cells Generated by Cohesion Defects and Placental Malformation

2007 Cell Cycle
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