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Jay L. Degen

Cincinnati Children's Hospital Medical Center
Hospital Research Foundation
University of Cincinnati Academic Health Center

172

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14523

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Host fibrinogen drives antimicrobial function in Staphylococcus aureus peritonitis through bacterial-mediated prothrombin activation.

2021 Proceedings of the National Academy of Sciences of the United States of America
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Citations (1)
Glial cells maintain synapses by inhibiting an activity-dependent retrograde protease signal

2019 PLOS Genetics
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A fibrin biofilm covers blood clots and protects from microbial invasion

2018 Journal of Clinical Investigation
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Plasminogen Deficiency Delays the Onset and Protects from Demyelination and Paralysis in Autoimmune Neuroinflammatory Disease

2017 The Journal of Neuroscience
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Plasmin Prevents Dystrophic Calcification after Muscle Injury.

2017 Journal of Bone and Mineral Research
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Genetic diminution of circulating prothrombin ameliorates multiorgan pathologies in sickle cell disease mice.

2015 Blood
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Transglutaminase factor XIII promotes arthritis through mechanisms linked to inflammation and bone erosion

2015 Blood
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Erratum: Fibrinolysis is essential for fracture repair and prevention of heterotopic ossification (Journal of Clinical Investigation (2015) 125: 9 (3723) DOI: 10.1172/JCI84059)

2015 Journal of Clinical Investigation
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Mice expressing a mutant form of fibrinogen that cannot support fibrin formation exhibit compromised antimicrobial host defense

2015 Blood
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Fibrinolysis is essential for fracture repair and prevention of heterotopic ossification.

2015 Journal of Clinical Investigation
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Citations (56)