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Darin Takemoto

Vertex Pharmaceuticals

12

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Deletion of the MAD2L1 spindle assembly checkpoint gene is tolerated in mouse models of acute T-cell lymphoma and hepatocellular carcinoma

2017 eLife
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Author response: Deletion of the MAD2L1 spindle assembly checkpoint gene is tolerated in mouse models of acute T-cell lymphoma and hepatocellular carcinoma

2017 eLife
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Abstract P5-06-05: Preclinical characterization of VX-984, a selective DNA-dependent protein kinase (DNA-PK) inhibitor in combination with doxorubicin in breast and ovarian cancers

2017 Cancer Research
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Abstract 3711: Pre-clinical combinations of ATR and PARP inhibitors: Defining target patient populations and dose schedule

2016 Cancer Research
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Preclinical characterization of the selective DNA-dependent protein kinase (DNA-PK) inhibitor VX-984 in combination with chemotherapy

2016 Annals of Oncology
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Abstract 1644: VX-970, the first-in-class inhibitor of the DNA damage repair enzyme ATR

2015 Cancer Research
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Potentiation of tumor responses to DNA damaging therapy by the selective ATR inhibitor VX-970

2014 Oncotarget
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Abstract 5491: Evaluation of the first potent and highly selective inhibitor of ATR kinase: An approach to selectively sensitize cancer cells to genotoxic drugs

2011 Cancer Research
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