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Charlie Degui Chen

Laboratory of Molecular Biology

21

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412

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PHF8-promoted TOPBP1 demethylation drives ATR activation and preserves genome stability.

2021 Science Advances
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Prediction of meiosis-essential genes based upon the dynamic proteomes responsive to spermatogenesis

2020 bioRxiv
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Lysine Demethylase PHF8-Promoted TOPBP1 Demethylation Drives ATR Activation and Contributes to Breast Tumorigenesis

2020 Social Science Research Network
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Critical role of histone H3 lysine 27 demethylase Kdm6b in the homeostasis and function of medullary thymic epithelial cells.

2020 Cell Death & Differentiation
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Prediction and validation of mouse meiosis-essential genes based on spermatogenesis proteome dynamics.

2020 Molecular & Cellular Proteomics
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5-hydroxymethylcytosine loss is associated with poor prognosis for patients with WHO grade II diffuse astrocytomas

2016 Scientific Reports
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Plant Homeo Domain Finger Protein 8 Regulates Mesodermal and Cardiac Differentiation of Embryonic Stem Cells Through Mediating the Histone Demethylation of pmaip1

2016 Stem Cells
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Id4 Marks Spermatogonial Stem Cells in the Mouse Testis.

2015 Scientific Reports
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Histone demethylase JMJD3 is required for osteoblast differentiation in mice

2015 Scientific Reports
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Expression profiles of histone lysine demethylases during cardiomyocyte differentiation of mouse embryonic stem cells

2014 Acta Pharmacologica Sinica
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