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Douglas S. Darling

University of Louisville

66

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ZEB1 promotes inflammation and progression towards inflammation-driven carcinoma through repression of the DNA repair glycosylase MPG in epithelial cells

2019 Gut
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ZEB1 protects skeletal muscle from damage and is required for its regeneration

2019 Nature Communications
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Regulation of muscle atrophy-related genes by the opposing transcriptional activities of ZEB1/CtBP and FOXO3

2018 Nucleic Acids Research
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PO-192 The emt factor zeb1 promotes adenoma formation through the inhibition of cell senescence and apoptosis

2018
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Interplay between Notch1 and Notch3 promotes EMT and tumor initiation in squamous cell carcinoma

2017 Nature Communications
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ZEB1 Regulates Multiple Oncogenic Components Involved in Uveal Melanoma Progression

2017 Scientific Reports
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ZEB1-induced tumourigenesis requires senescence inhibition via activation of DKK1/mutant p53/Mdm2/CtBP and repression of macroH2A1

2017 Gut
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Phosphorylation Regulates Functions of ZEB1 Transcription Factor

2016 Journal of Cellular Physiology
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ZEB1 targets multiple malignancy-related components to promote uveal melanoma cell dedifferentiation, proliferation, invasion, and metastasis

2016 Investigative Ophthalmology & Visual Science
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ZEB1 induces the Wnt antagonist DKK1 to jointly determine poorer survival in colorectal carcinomas

2016 European Journal of Cancer
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