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Karl B. Shpargel

University of North Carolina at Chapel Hill

28

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2400

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UTX promotes CD8+ T cell-mediated antiviral defenses but reduces T cell durability.

2021 Cell Reports
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The KMT2D Kabuki syndrome histone methylase controls neural crest cell differentiation and facial morphology

2020 Development
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HNF1A recruits KDM6A to activate differentiated acinar cell programs that suppress pancreatic cancer

2020 The EMBO Journal
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HNF1A recruits UTX to activate a differentiation program that suppresses pancreatic cancer

2019 bioRxiv
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UTX-guided neural crest function underlies craniofacial features of Kabuki syndrome

2017 Proceedings of the National Academy of Sciences of the United States of America
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The histone demethylase Kdm6b regulates a mature gene expression program in differentiating cerebellar granule neurons

2017 Molecular and Cellular Neuroscience
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KDM6 Demethylase Independent Loss of Histone H3 Lysine 27 Trimethylation during Early Embryonic Development

2014 PLOS Genetics
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An epigenetic switch induced by Shh signalling regulates gene activation during development and medulloblastoma growth

2014 Nature Communications
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UTX and UTY Demonstrate Histone Demethylase-Independent Function in Mouse Embryonic Development

2012 PLOS Genetics
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A noncoding point mutation of Zeb1 causes multiple developmental malformations and obesity in Twirler mice

2011 PLOS Genetics
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Citations (23)