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Tiow-Suan Sim

National University of Singapore

72

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852

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Co-chaperones of Hsp90 in Plasmodium falciparum and their concerted roles in cellular regulation.

2014 Parasitology
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Plasmodium falciparum possesses a unique dual-specificity serine/threonine and tyrosine kinase, Pfnek3

2012 Cellular and Molecular Life Sciences
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Molecular analysis of Plasmodium falciparum co-chaperone Aha1 supports its interaction with and regulation of Hsp90 in the malaria parasite.

2012 The International Journal of Biochemistry & Cell Biology
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Features of the Streptomyces hygroscopicus HtpG reveal how partial geldanamycin resistance can arise with mutation to the ATP binding pocket of a eukaryotic Hsp90

2011 The FASEB Journal
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Designing new β-lactams: implications from their targets, resistance factors and synthesizing enzymes.

2011 Current Computer - Aided Drug Design
- Kian-Sim Goo
- Tiow-Suan Sim
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Characterization of Plasmodium falciparum co-chaperone p23: its intrinsic chaperone activity and interaction with Hsp90

2010 Cellular and Molecular Life Sciences
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Regulation of Plasmodium falciparum Pfnek3 relies on phosphorylation at its activation loop and at threonine 82

2009 Cellular and Molecular Life Sciences
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Structural basis of the radicicol resistance displayed by a fungal hsp90

2009 ACS Chemical Biology
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Atypical caseinolytic protease homolog from Plasmodium falciparum possesses unusual substrate preference and a functional nuclear localization signal.

2009 Parasitology Research
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Relevant Double Mutations in Bioengineered Streptomyces clavuligerus Deacetoxycephalosporin C Synthase Result in Higher Binding Specificities Which Improve Penicillin Bioconversion

2008 Applied and Environmental Microbiology
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