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Alexander Hoepping

Georgetown University

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(+)-[ 18 F]Flubatine as a novel α4β2 nicotinic acetylcholine receptor PET ligand—results of the first-in-human brain imaging application in patients with β-amyloid PET-confirmed Alzheimer’s disease and healthy controls

2020 European Journal of Nuclear Medicine and Molecular Imaging
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Exploring the Metabolism of (+)-[18F]Flubatine In Vitro and In Vivo: LC-MS/MS Aided Identification of Radiometabolites in a Clinical PET Study †

2018 Molecules
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Image-Guided Development of Heterocyclic Sulfoxides as Ligands for Tau Neurofibrillary Tangles: From First-in-Man to Second-Generation Ligands

2018
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Procedures for the GMP-Compliant Production and Quality Control of [18F]PSMA-1007—A Next Generation Radiofluorinated Tracer for the Detection of Prostate Cancer

2017
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Procedures for the GMP-Compliant Production and Quality Control of [18F]PSMA-1007: A Next Generation Radiofluorinated Tracer for the Detection of Prostate Cancer

2017 Pharmaceuticals
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Radiopharmacology and PET of O-3-(2-[18F]fluoroethyl)-L-DOPA ([18F]OFED) - a new fluorine-18 labeled phenylalanine derivative

2016 The Journal of Nuclear Medicine
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LC-MS Supported Studies on the in Vitro Metabolism of both Enantiomers of Flubatine and the in Vivo Metabolism of (+)-[18F]Flubatine—A Positron Emission Tomography Radioligand for Imaging α4β2 Nicotinic Acetylcholine Receptors

2016 Molecules
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Radiation dosimetry of the α4β2 nicotinic receptor ligand (+)-[18F]flubatine, comparing preclinical PET/MRI and PET/CT to first-in-human PET/CT results

2016 EJNMMI Physics
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Enhanced copper-mediated 18F-fluorination of aryl boronic esters provides eight radiotracers for PET applications

2016 Chemical Communications
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First-in-man incorporation dosimetry of (+)-[18F]flubatine

2015 The Journal of Nuclear Medicine
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