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Immanuel F. Luescher

Ludwig Institute for Cancer Research
University of Lausanne

149

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7213

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Probing the Conformational Dynamics of Affinity-Enhanced T Cell Receptor Variants upon Binding the Peptide-Bound Major Histocompatibility Complex by Hydrogen/Deuterium Exchange Mass Spectrometry.

2021 Biochemistry
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CD8 binding of mhc-peptide complexes IN CIS or trans regulates CD8+ T cell responses

2019 Journal of Molecular Biology
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Improved process conditions for increasing expression of MHC class II protein from a stable Drosophila S2 cell line

2018 Biotechnology Letters
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In silico and cell-based analyses reveal strong divergence between prediction and observation of T-cell–recognized tumor antigen T-cell epitopes

2017 Journal of Biological Chemistry
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The T-Cell Receptor Can Bind to the Peptide-Bound Major Histocompatibility Complex and Uncomplexed β2-Microglobulin through Distinct Binding Sites

2017 Biochemistry
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Vaccination with LAG-3Ig (IMP321) and Peptides Induces Specific CD4 and CD8 T-Cell Responses in Metastatic Melanoma Patients—Report of a Phase I/IIa Clinical Trial

2016 Clinical Cancer Research
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Phospholipids enhance the binding of peptides to class II major histocompatibility molecules (immunogenicity/antigen presentation/antigen processing/antigen-presenting cells/lipids)

2016
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Identification and isolation of high avidity tumor-specific CD8 T cells by assessment of pMHC-TCR binding parameters with soluble pMHC complexes

2016 F1000Research
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Current tools for predicting cancer-specific T cell immunity

2016 OncoImmunology
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CD8 engineered cytotoxic T cells reprogram melanoma tumor environment

2016 OncoImmunology
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