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Chandra Sekhar Chirumamilla

University of Antwerp

18

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360

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The steroidal lactone withaferin A impedes T-cell motility by inhibiting the kinase ZAP70 and subsequent kinome signaling.

2021 Journal of Biological Chemistry
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Nano-targeted induction of dual ferroptotic mechanisms eradicates high-risk neuroblastoma

2018 Journal of Clinical Investigation
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Molecular biochemical characterization of selective glucocorticoid receptor activities of GSK866 analogues with cysteine reactive warheads

2018
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Imidazo[2,1-b]benzothiazol Derivatives as Potential Allosteric Inhibitors of the Glucocorticoid Receptor

2018 ACS Medicinal Chemistry Letters
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Epigenetic strategies to reverse drug resistance in heterogeneous multiple myeloma

2017 Clinical Epigenetics
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A systems biology network analysis of nutri(epi)genomic changes in endothelial cells exposed to epicatechin metabolites

2017
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Selective glucocorticoid receptor properties of GSK866 analogs with cysteine reactive warheads

2017 Frontiers in Immunology
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Withaferin A induces heme oxygenase (HO-1) expression in endothelial cells via activation of the Keap1/Nrf2 pathway

2016 Biochemical Pharmacology
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Ectopic microRNA-150-5p transcription sensitizes glucocorticoid therapy response in MM1S multiple myeloma cells but fails to overcome hormone therapy resistance in MM1R cells.

2014 PLOS ONE
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Chapter 10 – Connecting Phytochemicals, Epigenetics, and Healthy Aging: Is Metabolism the Missing Link?

2014
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