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Arnaud Pierre Jean Bourin

12

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191

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Abstract 53: Discovery of novel potent and orally bioavailable small-molecule inhibitors of ENPP1 to stabilize cGAMP and ATP in the tumor microenvironment and boost anti-tumor immunity

2021
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P016 GI restricted ROCK inhibitors show potential to treat fibrosis and stenosis associated with inflammatory bowel disease

2018 Journal of Crohns & Colitis
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Treatment of Intestinal Fibrosis in Experimental Inflammatory Bowel Disease by the Pleiotropic Actions of a Local Rho Kinase Inhibitor

2017 Gastroenterology
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Tetrahydro-pyrimido-indoles as selective LIMK inhibitors: synthesis, selectivity profiling and structure–activity studies

2016 MedChemComm
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Mo1762 Soft Rock Inhibition Prevents Intestinal Fibrosis in a Murine Colitis Model

2015 Gastroenterology
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Design, synthesis and biological characterization of selective LIMK inhibitors.

2015 Bioorganic & Medicinal Chemistry Letters
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Novel Roflumilast analogs as soft PDE4 inhibitors

2014 Bioorganic & Medicinal Chemistry Letters
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New inhibitors rock

2013
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Drug to Genome to Drug: Discovery of New Antiplasmodial Compounds

2011 Journal of Medicinal Chemistry
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