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John Bial

12

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342

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Metabolic characterization of the high-fat/high sucrose diet challenge in liver-humanized mice

2020 Atherosclerosis
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LBP-09-Liver humanization of Fah –/–/Rag2 –/–/Il2rg –/–andnbsp;NOD mice with human hepatocytes homozygous for M148I PNPLA3 allows the assessment of specific genotype contribution to NASH development in vivo.

2019 Journal of Hepatology
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New insights from liver‐humanized mice on cholesterol lipoprotein metabolism and LXR‐agonist pharmacodynamics in humans

2019 Hepatology
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Reduction Of Bile Acid Synthesis And Intrahepatic Lipid Accumulation In Liver-Humanized Mice Define The Unfavorable Pharmacodynamics Of Lxr Agonism In Humans

2019 Atherosclerosis
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Assessing drug efficacy against Plasmodium falciparum liver stages in vivo

2018 JCI insight
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Successful engraftment of human hepatocytes in uPA- SCID and FRG® KO mice

2017 Methods of Molecular Biology
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Murine model of hepatic breast cancer

2016 Biochemistry and biophysics reports
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Extensive double humanization of both liver and hematopoiesis in FRGN mice

2014 Stem Cell Research
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