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Heike Thomas

University of Exeter

9

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Tissue-specific transcription factor HNF4alpha inhibits cell proliferation and induces apoptosis in the pancreatic INS-1 beta-cell line.

2007 Biological Chemistry
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Conditional expression of hepatocyte nuclear factor-1β, the maturity-onset diabetes of the young-5 gene product, influences the viability and functional competence of pancreatic β-cells

2006 Journal of Endocrinology
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Pattern of genes influenced by conditional expression of the transcription factors HNF6, HNF4α and HNF1β in a pancreatic β-cell line

2004 Nucleic Acids Research
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Evidence for Haploinsufficiency of the Human HNF1α Gene Revealed by FunctionalCharacterization of MODY3-AssociatedMutations

2002 Biological Chemistry
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A distant upstream promoter of the HNF-4α gene connects the transcription factors involved in maturity-onset diabetes of the young

2001 Human Molecular Genetics
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Naturally occurring mutations in the human HNF4α gene impair the function of the transcription factor to a varying degree

2000 Nucleic Acids Research
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Citations (63)