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Peter J. H. Webborn

Loughborough University

18

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873

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Actives from MMV Open Access Boxes? A suggested way forward.

2021 PLOS Pathogens
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CHAPTER 8:Prediction of Human Pharmacokinetics, Exposure and Therapeutic Dose in Drug Discovery

2014
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Scaffold-hopping with zwitterionic CCR3 antagonists: identification and optimisation of a series with good potency and pharmacokinetics leading to the discovery of AZ12436092.

2012 Bioorganic & Medicinal Chemistry Letters
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Discovery and evolution of phenoxypiperidine hydroxyamide dual CCR3/H1 antagonists. Part II: Optimising in vivo clearance

2012 Bioorganic & Medicinal Chemistry Letters
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Discovery and evolution of phenoxypiperidine hydroxyamide dual CCR3/H1 antagonists. Part I

2012 Bioorganic & Medicinal Chemistry Letters
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Hepatic Uptake in the Dog: Comparison of Uptake in Hepatocytes and Human Embryonic Kidney Cells Expressing Dog Organic Anion-Transporting Polypeptide 1B4

2011 Drug Metabolism and Disposition
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Impact of hepatic uptake transporters on pharmacokinetics and drug-drug interactions: use of assays and models for decision making in the pharmaceutical industry.

2009 Molecular Pharmaceutics
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Functional Consequences of Active Hepatic Uptake on Cytochrome P450 Inhibition in Rat and Human Hepatocytes

2008 Drug Metabolism and Disposition
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Design of Helicobacter pylori glutamate racemase inhibitors as selective antibacterial agents: a novel pro-drug approach to increase exposure.

2008 Bioorganic & Medicinal Chemistry Letters
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In vitro-in vivo extrapolation of hepatic clearance involving active uptake: theoretical and experimental aspects.

2007 Xenobiotica
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Citations (59)