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Janice Darlington

Gazi University

18

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443

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Identification of 4-(Aminomethyl)-6-(trifluoromethyl)-2-(phenoxy)pyridine Derivatives as Potent, Selective, and Orally Efficacious Inhibitors of the Copper-Dependent Amine Oxidase, Lysyl Oxidase-Like 2 (LOXL2)

2017 Journal of Medicinal Chemistry
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Small Molecule Lysyl Oxidase-like 2 (LOXL2) Inhibitors: The Identification of an Inhibitor Selective for LOXL2 over LOX

2017 ACS Medicinal Chemistry Letters
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Selective Inhibition of Autotaxin Is Efficacious in Mouse Models of Liver Fibrosis.

2016 Journal of Pharmacology and Experimental Therapeutics
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Structural Basis for Inhibition of Human Autotaxin by Four Potent Compounds with Distinct Modes of Binding.

2015 Molecular Pharmacology
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Pharmacokinetic and Pharmacodynamic Characterization of an Oral Lysophosphatidic Acid Type 1 Receptor-Selective Antagonist

2011 Journal of Pharmacology and Experimental Therapeutics
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Synthesis of 1,5-Diarylpyrazol-3-propanoic Acids Towards Inhibition of Cyclooxygenase-1/2 Activity and 5-Lipoxygenase-Mediated LTB4 Formation.

2011 Drug Research
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Pharmacology of AM211, a Potent and Selective Prostaglandin D2 Receptor Type 2 Antagonist That Is Active in Animal Models of Allergic Inflammation

2011 Journal of Pharmacology and Experimental Therapeutics
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Pharmacology of AM211, a potent and selective DP2 receptor antagonist that is active in animal models of allergic inflammation

2011 Journal of Pharmacology and Experimental Therapeutics
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The 5-Lipoxygenase-Activating Protein (FLAP) Inhibitor GSK2190915 , Reduces Cigarette Smoke-Induced Pulmonary Inflammation In The Mouse

2011 ATS | American Thoracic Society International Conference
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Synthesis of 1,5-Diarylpyrazol-3-propanoic Acids Towards Inhibition of Cyclooxygenase-1/2 Activity and 5-Lipoxygenase-Mediated LTB4 Formation.

2010 ChemInform
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