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Nikolaos Trasanidis

Imperial College London

17

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8

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Systems medicine dissection of chromosome 1q amplification reveals oncogenic regulatory circuits and informs targeted therapy in cancer

2021 bioRxiv
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Chromatin-based, in cis and in trans regulatory rewiring underpins distinct oncogenic transcriptomes in multiple myeloma

2021 Nature Communications
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Brd2/4 and Myc regulate alternative cell lineage programmes during early osteoclast differentiation in vitro.

2021 iScience
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The innate sensor ZBP1-IRF3 axis regulates cell proliferation in multiple myeloma

2021 Haematologica
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Current progress and potential opportunities to infer single-cell developmental trajectory and cell fate

2021 Current Opinion in Systems Biology
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The innate sensor ZBP1-IRF3 axis regulates cell proliferation in multiple myeloma

2020 bioRxiv
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Over-accessible chromatin links myeloma initiating genetic events to oncogenic transcriptomes and aberrant transcription factor regulatory networks

2020 bioRxiv
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Single-Cell Transcriptional Landscapes of Human Bone Marrow Reveal Distinct Erythroid Phenotypes Underpinned By Genotype in Diamond-Blackfan Anemia

2020 Blood
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Novel ZBP1-IRF3 Dependency in Multiple Myeloma Mediated By IRF3-Driven Regulation of Cell Cycle Genes

2019 Blood
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Oncogenic MAF in Co-Operation with IRF4 Confers Extensive Chromatin Re-Arrangement in Plasma Cells and Generates ‘Neo-Enhancers’ That Regulate Genes Critical for Myeloma Biology

2019 Blood
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