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Diarmaid Hughes

Uppsala University

204

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10216

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Phenotypic and genetic barriers to establishment of horizontally transferred genes encoding ribosomal protection proteins.

2021 Journal of Antimicrobial Chemotherapy
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Urinary pH Warrants Therapeutic Window of EBL-1003 (Apramycin) in the Treatment of Complicated Urinary Tract Infections and Acute Pyelonephritis

2021 Social Science Research Network
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Evaluating the potential efficacy and limitations of a phage for joint antibiotic and phage therapy of Staphylococcus aureus infections.

2021 Proceedings of the National Academy of Sciences of the United States of America
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Antibacterial activity of apramycin at acidic pH warrants wide therapeutic window in the treatment of complicated urinary tract infections and acute pyelonephritis.

2021 EBioMedicine
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Antibacterial sulfonimidamide-based oligopeptides as type I signal peptidase inhibitors: Synthesis and biological evaluation.

2021 European Journal of Medicinal Chemistry
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ENABLE: an engine for European antibacterial drug discovery and development.

2021 Nature Reviews Drug Discovery
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The SNAP hypothesis: Chromosomal rearrangements could emerge from positive Selection during Niche Adaptation

2020 PLOS Genetics
- Gerrit Brandis
- Diarmaid Hughes
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Population bottlenecks strongly influence the evolutionary trajectory to fluoroquinolone resistance in Escherichia coli

2020 Molecular Biology and Evolution
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Structure-Activity Relationship Studies on the Inhibition of the Bacterial Translation of Novel Odilorhabdins Analogues

2020 Bioorganic & Medicinal Chemistry
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Joint antibiotic and phage therapy: addressing the limitations of a seemingly ideal phage for treating Staphylococcus aureus infections

2020 bioRxiv
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