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Robert O. Carlson

Bayer

17

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158

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Combined activity of the cancer metabolism inhibitor MPC-8640 and 5-fluorouracil in xenograft models.

2017 Journal of Clinical Oncology
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Abstract 1756: Preclinical activity in non-Hodgkin's lymphoma of Selinexor, a selective inhibitor of nuclear export (SINE), is enhanced through combination with standard-of-care therapies

2015 Cancer Research
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Lead optimization of purine based orally bioavailable Mps1 (TTK) inhibitors.

2012 Bioorganic & Medicinal Chemistry Letters
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Characterization of the Cellular and Antitumor Effects of MPI-0479605, a Small-Molecule Inhibitor of the Mitotic Kinase Mps1

2011 Molecular Cancer Therapeutics
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Abstract 3526: Coadministration of nicotinic acid with the Nampt inhibitor MPC-9528 enhances antitumor activity in Naprt deficient cancer cells in culture and in xenografts

2011 Cancer Research
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Abstract LB-393: The cancer metabolism inhibitor MPC-9528 induces tumor regression in xenograft models with multiple dosing schedules by causing rapid and sustained reduction in tumor NAD

2011 Cancer Research
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Abstract 2617: MPC-3100, a synthetic Hsp90 inhibitor, induces biomarker changes in vitro and in vivo

2011 Cancer Research
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Abstract 2628: Antitumor activity of MPC-3100, a synthetic Hsp90 inhibitor, in combination with erlotinib and sorafenib

2011 Cancer Research
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Abstract 577: Basal NAD levels and Nampt expression correlate with in vitro and in vivo sensitivity of tumor cell lines to the Nampt inhibitor MPC-9528

2011 Cancer Research
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Comparison of MPC-6827 activity in xenograft models with different dosing schedules.

2011 Journal of Clinical Oncology
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