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Edgar Specker

University of Marburg

25

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274

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Topical inflammasome inhibition with disulfiram prevents irritant contact dermatitis

2021 Clinical and Translational Allergy
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Enhanced Properties of a Benzimidazole Benzylpyrazole Lysine Demethylase Inhibitor: Mechanism-of-Action, Binding Site Analysis, and Activity in Cellular Models of Prostate Cancer.

2021 Journal of Medicinal Chemistry
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Crystal Structure of KDM4A with compound YP-02-145

2019
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Crystal Structure of KDM4A with compound YP-03-038

2019
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EU-OPENSCREEN: A Novel Collaborative Approach to Facilitate Chemical Biology:

2019
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Statin and rottlerin small-molecule inhibitors restrict colon cancer progression and metastasis via MACC1

2017 PLOS Biology
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Pharmacological restoration and therapeutic targeting of the B-cell phenotype in classical Hodgkin lymphoma

2017 Blood
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Identification of a Novel Benzimidazole Pyrazolone Scaffold That Inhibits KDM4 Lysine Demethylases and Reduces Proliferation of Prostate Cancer Cells

2017
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A Small-Molecule Antagonist of the β-Catenin/TCF4 Interaction Blocks the Self-Renewal of Cancer Stem Cells and Suppresses Tumorigenesis

2016 Cancer Research
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Sustainable synthesis and automated deposition: an accessible discovery screening library of fragment-like purines

2012 Molecular Diversity
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