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David S. Askew

University of Cincinnati Academic Health Center
University of Cincinnati

78

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Testing Inhibitory Drugs of the Human UPR Sensor IRE1 on Aspergillus fumigatus

2020 The FASEB Journal
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Functional Coupling between the Unfolded Protein Response and Endoplasmic Reticulum/Golgi Ca2+-ATPases Promotes Stress Tolerance, Cell Wall Biosynthesis, and Virulence of Aspergillus fumigatus.

2020 Mbio
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A Human IRE1 Inhibitor Blocks the Unfolded Protein Response in the Pathogenic Fungus Aspergillus fumigatus and Suggests Noncanonical Functions within the Pathway.

2020
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The Toxicity of a Novel Antifungal Compound Is Modulated by Endoplasmic Reticulum-Associated Protein Degradation Components

2016 Antimicrobial Agents and Chemotherapy
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Polysome profiling reveals broad translatome remodeling during endoplasmic reticulum (ER) stress in the pathogenic fungus Aspergillus fumigatus

2014 BMC Genomics
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Endoplasmic reticulum stress and fungal pathogenesis converge

2014 Virulence
- David S. Askew
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The fungal UPR: a regulatory hub for virulence traits in the mold pathogen Aspergillus fumigatus.

2014 Virulence
- Karthik Krishnan
- David S. Askew
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Advances Against Aspergillosis: Biology, Host response, Diagnosis and Treatment

2014 Mycopathologia
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Deletion of the sec4 Homolog srgA from Aspergillus fumigatus Is Associated with an Impaired Stress Response, Attenuated Virulence and Phenotypic Heterogeneity

2013 PLOS ONE
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Effects of a Defective Endoplasmic Reticulum-Associated Degradation Pathway on the Stress Response, Virulence, and Antifungal Drug Susceptibility of the Mold Pathogen Aspergillus fumigatus

2013 Eukaryotic Cell
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