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Benjamin G. Richardson
Benjamin G. Richardson
University of Illinois at Chicago
Biochemistry
Chemistry
Activator (genetics)
KEAP1
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6
Papers
158
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Isoquinoline Kelch-like ECH-Associated Protein 1-Nuclear Factor (Erythroid-derived 2)-like 2 (KEAP1-NRF2) Inhibitors with High Metabolic Stability
2019
Journal of Medicinal Chemistry
Phillip R. Lazzara
Brian P. David
Aparna Ankireddy
Benjamin G. Richardson
Katherine Dye
Kiira Ratia
Sekhar P. Reddy
Terry W. Moore
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Citations (20)
Crystal structure of N-(4-((4-methoxy-N-(2,2,2-trifluoroethyl)phenyl)sulfonamido)isoquinolin-1-yl)-N-((4-methoxyphenyl)sulfonyl)glycine bound to human Keap1 Kelch domain
2019
Phillip R. Lazzara
Brian P. David
A. Ankireddy
Benjamin G. Richardson
Katherine Dye
Kiira Ratia
Sekhar P. Reddy
Terry W. Moore
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Replacement of a Naphthalene Scaffold in Kelch-like ECH-Associated Protein 1 (KEAP1)/Nuclear Factor (Erythroid-derived 2)-like 2 (NRF2) Inhibitors
2018
Journal of Medicinal Chemistry
Benjamin G. Richardson
Atul D. Jain
Haranatha R. Potteti
Phillip R. Lazzara
Brian P. David
Chandra R. Tamatam
Ewelina Choma
Kornelia Skowron
Katherine Dye
Zamia Siddiqui
Yue Ting Wang
Aleksej Krunic
Sekhar P. Reddy
Terry W. Moore
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Citations (21)
Non-electrophilic modulators of the canonical Keap1/Nrf2 pathway
2015
Bioorganic & Medicinal Chemistry Letters
Benjamin G. Richardson
Atul D. Jain
Thomas E. Speltz
Terry W. Moore
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Citations (53)
Probing the structural requirements of non-electrophilic naphthalene-based Nrf2 activators.
2015
European Journal of Medicinal Chemistry
Atul D. Jain
Haranatha R. Potteti
Benjamin G. Richardson
Laura J. Kingsley
Julia P. Luciano
Aya F. Ryuzoji
Hyun Lee
Aleksej Krunic
Andrew D. Mesecar
Sekhar P. Reddy
Terry W. Moore
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Citations (56)
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