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Pu Paul Liu

National Institutes of Health

45

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RUNX1 and CBFβ-SMMHC transactivate target genes together in abnormal myeloid progenitors for leukemia development.

2020 Blood
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Splicing factor DHX15 affects tp53 and mdm2 expression via alternate splicing and promoter usage

2019 Human Molecular Genetics
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RUNX1 positively regulates the ErbB2/HER2 signaling pathway through modulating SOS1 expression in gastric cancer cells

2018 Scientific Reports
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Autonomous feedback loop of RUNX1-p53-CBFB in acute myeloid leukemia cells

2017 Scientific Reports
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Paradoxical enhancement of leukemogenesis in acute myeloid leukemia with moderately attenuated RUNX1 expressions

2017 Blood Advances
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RUNX1 and CBFB-MYH11 Are Required for the Maintenance of Inv(16) AML

2016 Blood
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The Roles of RUNX1 in Human Hematopoiesis and Megakaryopoiesis Revealed By Genome-Targeted Human iPSCs and an Improved Hematopoietic Differentiation Model

2015 Blood
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Targeted correction Of RUNX1 Mutation In The FPD Patient-Specific Induced Pluripotent Stem Cells Restores Megakaryocytic Differentiation

2013 Blood
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KIT with D816 mutations cooperates with CBFB-MYH11 for leukemogenesis in mice

2012 Blood
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Runx1 regulates embryonic myeloid fate choice in zebrafish through a negative feedback loop inhibiting Pu.1 expression

2012 Blood
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