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Takashi Ichikawa

Takeda Pharmaceutical Company

20

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468

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Nonbisphosphonate inhibitors of Plasmodium falciparum FPPS/GGPPS.

2021 Bioorganic & Medicinal Chemistry Letters
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Structure-based design and SAR development of 5,6-dihydroimidazolo[1,5-f]pteridine derivatives as novel Polo-like kinase-1 inhibitors.

2017 Bioorganic & Medicinal Chemistry Letters
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Optically Active Antifungal Azoles. Part 12. Synthesis and Antifungal Activity of the Water-Soluble Prodrugs of 1-[(1R,2R)-2-(2,4-Difluorophenyl)-2-hydroxy-1-methyl-3- (1H-1,2,4-triazol-1-yl)propyl]-3- [4-(1H-1-tetrazolyl)phenyl]-2-im

2010 ChemInform
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Discovery of a piperidine-4-carboxamide CCR5 antagonist (TAK-220) with highly potent Anti-HIV-1 activity.

2006 Journal of Medicinal Chemistry
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Optically Active Cyclohexene Derivative as a New Antisepsis Agent: An Efficient Synthesis of Ethyl (6R)-6-[N-(2-Chloro-4-fluorophenyl)sulfamoyl]cyclohex-1-ene-1-carboxylate (TAK-242)

2006 Chemical & Pharmaceutical Bulletin
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Optically Active Cyclohexene Derivative as a New Antisepsis Agent: An Efficient Synthesis of Ethyl (6R)-6-[N-(2-Chloro-4-fluorophenyl)sulfamoyl]cyclohex-1-ene-1-carboxylate (TAK-242)

2006 Chemical & Pharmaceutical Bulletin
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CCR5 antagonists as anti-HIV-1 agents. Part 3: Synthesis and biological evaluation of piperidine-4-carboxamide derivatives

2005 Bioorganic & Medicinal Chemistry
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CCR5 antagonists as anti-HIV-1 agents. Part 2: Synthesis and biological evaluation of N-[3-(4-benzylpiperidin-1-yl)propyl]-N,N′-diphenylureas

2004 Bioorganic & Medicinal Chemistry
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Efficacy of TAK-457, a Novel Intravenous Triazole, against Invasive Pulmonary Aspergillosis in Neutropenic Mice

2002 Antimicrobial Agents and Chemotherapy
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Optically Active Antifungal Azoles. XII. Synthesis and Antifungal Activity of the Water-Soluble Prodrugs of 1-[(1R, 2R)-2-(2, 4-Difluorophenyl)-2-hydroxy-1-methyl-3-(1H-1, 2, 4-triazol-1-yl)propyl]-3-[4-(1H-1-tetrazolyl)phenyl]-2-imidazolidinone

2001 Chemical & Pharmaceutical Bulletin
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Citations (29)