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Shigeki Seto

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Discovery of novel pyrazolo[1,5-a]pyridine-based EP1 receptor antagonists by scaffold hopping: Design, synthesis, and structure-activity relationships

2017 Bioorganic & Medicinal Chemistry Letters
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Identification of novel 1,2,3,6-tetrahydropyridyl-substituted benzo[d]thiazoles: Lead generation and optimization toward potent and orally active EP1 receptor antagonists

2017 Bioorganic & Medicinal Chemistry
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PBr3-Mediated Unexpected Reductive Deoxygenation of α-Aryl-pyridinemethanols: Synthesis of Arylmethylpyridines.

2016 ChemInform
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PBr3-mediated unexpected reductive deoxygenation of α-aryl-pyridinemethanols: synthesis of arylmethylpyridines

2016 Tetrahedron
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Quinolone derivatives containing strained spirocycle as orally active glycogen synthase kinase 3β (GSK-3β) inhibitors for type 2 diabetics.

2012 Bioorganic & Medicinal Chemistry
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Synthesis and structure-activity relationship of 4-quinolone-3-carboxylic acid based inhibitors of glycogen synthase kinase-3β.

2011 Bioorganic & Medicinal Chemistry Letters
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Design, Synthesis, and Structure−Activity Relationship Studies of Novel 2,4,6-Trisubstituted-5-pyrimidinecarboxylic Acids as Peroxisome Proliferator-Activated Receptor γ (PPARγ) Partial Agonists with Comparable Antidiabetic Efficacy to Rosiglitazone

2010 Journal of Medicinal Chemistry
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Chemoselective displacement of methylsulfinyl group with amines to provide 2-alkylamino-4,6-disubstituted pyrimidine-5-carboxylic acid

2009 Heterocycles
- Shigeki Seto
- Yasushi Kohno
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Aminoquinoloner as GSK-3 inhibitors

2007
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Aminoquinolonas as inhibitors of GSK-3

2007
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