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Jih-Lie Tseng

University of Western Ontario

10

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Reversible, orally available ADP receptor (P2Y12) antagonists Part I: Hit to lead process

2018 Bioorganic & Medicinal Chemistry Letters
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Novel P2Y12 adenosine diphosphate receptor antagonists for inhibition of platelet aggregation (I): In vitro effects on platelets

2008 Thrombosis Research
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Discovery of novel and potent aryl diamines as leukotriene A4 hydrolase inhibitors

2008 Bioorganic & Medicinal Chemistry Letters
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CCR5 receptor antagonists: Discovery and SAR of novel 4-hydroxypiperidine derivatives

2007 Bioorganic & Medicinal Chemistry Letters
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1-(1,3-Benzodioxol-5-ylmethyl)-3-[4-(1H-imidazol-1-yl)phenoxy]-piperidine analogs as potent and selective inhibitors of nitric oxide formation.

2007 Bioorganic & Medicinal Chemistry Letters
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Fasudil, a Rho-Kinase Inhibitor, Attenuates Angiotensin II–Induced Abdominal Aortic Aneurysm in Apolipoprotein E–Deficient Mice by Inhibiting Apoptosis and Proteolysis

2005 Circulation
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Anti-tumor efficacy of the nucleoside analog 1-(2-deoxy-2-fluoro-4-thio-β-D-arabinofuranosyl) cytosine (4′-thio-FAC) in human pancreatic and ovarian tumor xenograft models

2005 International Journal of Cancer
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Measurements of drug-protein binding by using immobilized human serum albumin liquid chromatography-mass spectrometry

2004 Journal of Chromatography B
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Novel 3-oxa lipoxin A4 analogues with enhanced chemical and metabolic stability have anti-inflammatory activity in vivo.

2004 Journal of Medicinal Chemistry
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A β-oxidation-resistant lipoxin A4 analog treats hapten-induced colitis by attenuating inflammation and immune dysfunction

2004 Proceedings of the National Academy of Sciences of the United States of America
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