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Gary D. Brayer

University of British Columbia

148

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6552

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Synthesis of Montbretin A Analogues Yields Potent Competitive Inhibitors of Human Pancreatic α-Amylase

2019 Chemical Science
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Folding Then Binding vs. Folding Through Binding in Macrocyclic Peptide Inhibitors of Human Pancreatic α-Amylase

2019 ACS Chemical Biology
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Ivermectin inhibits HSP27 and potentiates efficacy of oncogene targeting in tumor models

2019 Journal of Clinical Investigation
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Crystal stucture of human Cathepsin K with a non-active site inhibitor at 1.42 Angstrom resolution

2018
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Identification of mouse cathepsin K structural elements that regulate the potency of odanacatib.

2017 Biochemical Journal
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Crystal structure of mouse cathepsin K at 2.9 Angstroms resolution.

2017
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Rapid Discovery of Potent and Selective Glycosidase-Inhibiting De Novo Peptides

2017 Chemistry & Biology
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Crystal structure of Cathepsin K with a covalently-linked inhibitor at 1.4 Angstrom resolution.

2017
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Glucose lowering effect of montbretin A in Zucker Diabetic Fatty rats

2016 Molecular and Cellular Biochemistry
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Glucosyl epi‐cyclophellitol allows mechanism‐based inactivation and structural analysis of human pancreatic α‐amylase

2016 FEBS Letters
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Citations (17)