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Shan Yu

The Chinese University of Hong Kong

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Nuclear receptor ERRα contributes to castration-resistant growth of prostate cancer via its regulation of intratumoral androgen biosynthesis

2020 Theranostics
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Nuclear receptor HNF4α performs a tumor suppressor function in prostate cancer via its induction of p21-driven cellular senescence.

2019 Oncogene
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Orphan nuclear receptor TLX contributes to androgen insensitivity in castration-resistant prostate cancer via its repression of androgen receptor transcription

2018 Oncogene
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Nuclear receptor ERRα and transcription factor ERG form a reciprocal loop in the regulation of TMPRSS2:ERG fusion gene in prostate cancer

2018 Oncogene
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Nuclear Receptor LRH-1 Functions to Promote Castration-Resistant Growth of Prostate Cancer via Its Promotion of Intratumoral Androgen Biosynthesis

2018 Cancer Research
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Collapsin response mediator protein-1 (CRMP1) acts as an invasion and metastasis suppressor of prostate cancer via its suppression of epithelial–mesenchymal transition and remodeling of actin cytoskeleton organization

2017 Oncogene
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Orphan nuclear receptor TLX functions as a potent suppressor of oncogene-induced senescence in prostate cancer via its transcriptional co-regulation of the CDKN1A (p21WAF1/CIP1) and SIRT1 genes

2015 The Journal of Pathology
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Abstract 1385: Orphan nuclear receptor estrogen-related receptor alpha (ERRα) characterized as a novel transcriptional regulator of the oncogenic fusion gene TMPRSS2:ERG in prostate cancer

2014 Cancer Research
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ERRα augments HIF‐1 signalling by directly interacting with HIF‐1α in normoxic and hypoxic prostate cancer cells

2014 The Journal of Pathology
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Estrogen-related receptor α decreases RHOA stability to induce orientated cell migration.

2014 Proceedings of the National Academy of Sciences of the United States of America
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